Scientific Staff Profiles

This page allows you to read information about people engaged in research at CAMH. You can search for researchers using the name or keyword search engine below.

Dr. Art Petronis Krembil Family Epigenetics Laboratory Centre for Addiction and Mental Health 250 College Street Toronto, Ontario M5T 1R8 (416) 535-8501 ext. 4880 arturas_petronis@camh.net Dr. Arturas Petronis is a Senior Scientist in the Neuroscience Department and Head of the Krembil Family Epigenetics Laboratory. He is an Associate Professor with the Department of Psychiatry at the University of Toronto. Search again?
Areas of Research Dr. Petronis has launched a comprehensive epigenetics research program in the Krembil family Epigenetics Laboratory. This section is developing new techniques and tools to search the entire genome for gene modifications that have been identified as epigenetic risk factors. These factors are believed to play a role in the manifestation of psychiatric and other illnesses, in addition to genetic and environmental influences. Epigenetics research shows that regulation of gene activity is critically important for normal functioning of the genome. The technology may help to identify the causes of complex diseases such as schizophrenia, diabetes, and cancer, and open new avenues for developing novel diagnostic and therapeutic approaches.
Publications Mill J, Yazdanpanah S, Gückel E, Ziegler S, Kaminsky ZA, Petronis A. Whole-genome amplification (WGA) of sodium bisulfite-treated DNA allows the accurate estimate of methylated cytosine density in limited DNA resources. BioTechniques. 2006. In press. Kaminsky ZA, Wang SC, Petronis A. Complex Disease, Gender, and Epigenetics. Annals of Medicine. 2006. In press. Flanagan J, Popendikyte V, Pozdniakovaite N, Sobolev M, Assadzadeh A, Schumacher A, Zangeneh M, Lau L, Virtanen C, Wang S-C, Petronis A. Intra- and Inter- Individual Epigenetic Variation in Human Germ Cells. American Journal of Human Genetics, 2006;79(1):67-84. Schumacher A, Kapranov P, Kaminsky ZA, Flanagan J, Assadzadeh A, Yau P, Virtanen C, Winegarden N, Cheng J, Gingeras T, Petronis A. Microarray-based DNA Methylation Profiling: Technology and Applications. Nucleic Acid Research. 2006;34(2):528-42. Schumacher A, Petronis A. Epigenetics of Complex Disease: from the General Theory to Laboratory Experiment. Current Topics in Microbiology and Immunology. 2006;310:81-115. Wong AH, Gottesman II, Petronis A. Phenotypic differences in genetically identical organisms: the epigenetic perspective. Human Molecular Genetics. 14 Suppl. 2005;1:R11-8. Kaminsky ZA, Popendikyte V, Assadzadeh A, and Petronis A. Search for somatic DNA variation in the brain: investigation of the serotonin 2A receptor gene. Mammalian Genome. 2005;16(8):587-93. Kaminsky ZA, Assadzadeh A, Flanagan J, and Petronis A. Single Nucleotide Extension Technology for Quantitative Site Specific Evaluation of metC/C in GC-Rich Regions. Nucleic Acid Research. 2005;33(10): e95. Petronis A. Epigenetics and Twins: Three Variations on the Theme. Trends in Genetics. 2005;22(7):347-50. Sivagnanasundaram S, Broman KW, Liu M, Petronis A. Quasi-linkage: a confounding factor in linkage analysis of complex diseases? Human Genetics. 2004;114(6): 588-93.
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