Scientific Staff Profiles

This page allows you to read information about people engaged in research at CAMH. You can search for researchers using the name or keyword search engine below.

Dr. Z. Jeff Daskalakis Schizophrenia Program Centre for Addiction and Mental Health 250 College Street Toronto, Ontario M5T 1R8 (416) 535-8501 ext. 4319 jeff_daskalakis@camh.net Z. Jeff Daskalakis, MD, PhD, FRCP, is a Staff Psychiatrist with the Schizophrenia Program, Director of the Brain Stimulation Treatment and Research Program, Research Section Head for the Schizophrenia Program and an Associate Professor of Psychiatry in the Department of Psychiatry at the University of Toronto. Dr. Daskalakis has been a NARSAD Lieber Young Investigator, a NARSAD Independent Investigator, and holds both a Canadian Institutes of Health Research Clinician Scientist  and OMHF Research award.  Search again?
Areas of Research As an expert on the neurophysiology of severe pyschiatric disorders,  Dr. Daskalakis' research laboratory uses magnetic brain stimulation to study the role of cortical inhibition and plasticity as potential pathophysiological mechanisms in schizophrenia and depression. Dr. Daskalakis also conducts treatment studies using repetitive transcranial magnetic brain stimulation (rTMS ) for refractory symptoms in these disorders and he leads the rTMS alternative treatment strategy for establishing new and more effective interventions in resistant psychiatric disorders. He has over 65 peer-reviewed publications in journals including the Archives of General Psychiatry and the American Journal of Psychiatry.
Publications Fitzgerald PB, Hoy K, McQueen S, Maller JJ, Herring S, Segrave R, Bailey M, Been G, Kulkarni J, Daskalakis ZJ. A Randomized Trial of rTMS Targeted with MRI Based Neuro-Navigation in Treatment Resistant Depression. Neuropsychopharmacology. 2009 Jan 14. [Epub ahead of print]   Farzan F, Barr MS, Wong W, Chen R, Fitzgerald PB, Daskalakis ZJ: Suppression of Gamma Oscillation in the DLPFC following Long Interval Cortical Inhibition: a TMS-EEG Study: a TMS-EEG Study, Neuropsychopharmacology, 2008 Nov 26. [Epub ahead of print]   Liu SK, Fitzgerald PB, Daigle M, Chen R, Daskalakis ZJ: The Relationship between Cortical Inhibition, Antipsychotic Treatment and the Symptoms of Schizophrenia. Biological Psychiatry, 2009 Feb 15;65(4):313-8. Epub 2008 Sep 27.   Daskalakis ZJ, Levinson AJ, Fitzgerald PB: Repetitive Transcranial Magnetic Stimulation for Major Depressive Disorder: A Review. Canadian Journal of Psychiatry, 2008 Sep;53(9):555-66.   Fitzgerald PB, Daskalakis ZJ: A review of the use of repetitive transcranial magnetic stimulation in the treatment of schizophrenia. Canadian Journal of Psychiatry, 2008 Sep;53(9):567-76.   Daskalakis ZJ, Farzan F, Barr MS, Maller JJ, Chen R, Fitzgerald PB: Long Interval Cortical Inhibition from the Dorsolateral Prefrontal Cortex: A TMS-EEG Study, Neuropsychopharmacology. 2008 Nov;33(12):2860-9. Epub 2008 Mar 5.   Daskalakis ZJ, Christensen BK, Fitzgerald PB, Chen R. Dysfunctional Neural Plasticity in Patients with Schizophrenia. Archives of General Psychiatry. 2008; 65(4):378-385.   Daskalakis ZJ, Fitzgerald PB, Christensen BK. The Role of Cortical Inhibition in the Pathophysiology and Treatment of Schizophrenia. Brain Research Reviews, in press (accepted September 2007).   Frantseva M, Fitzgerald PB, Chen R,Möller BM,Daigle M, Daskalakis ZJ. Evidence for Impaired Long-Term Potentiation in Schizophrenia and its Relationship to Motor Skill Leaning. Cerebral Cortex. 2007 Sep 12; [Epub ahead of print].   Levinson AJ, Young LT, Fitzgerald PB, Daskalakis ZJ. Cortical Inhibitory Dysfunction in Bipolar Disorder: A Study using Transcranial Magnetic Stimulation (TMS). J Clin Psychopharmacol. 2007 Oct;27(5):493-497.   Daskalakis ZJ, Christensen BK, Fitzgerald PB, Möller BM, Fountain SI, Chen R. Increased Cortical Inhibition in Persons with Schizophrenia Treated with Clozapine. Journal of Psychopharmacology, in press (accepted October 2006).    Daskalakis ZJ, Möller BM, Christensen BK, Fitzgerald PB, Gunraj C, Chen R. The Effects of Repetitive Transcranial Magnetic Stimulation on Cortical Inhibition in Healthy Human Subjects. Experimental Brain Research. Oct 2006;174(3):403-12.   Daskalakis ZJ, Christensen BK, Fitzgerald PB, Fountain SI, Chen R. Reduced Cerebellar Inhibition in Schizophrenia: A Preliminary Study. American Journal of Psychiatry. 2005 Jun;162:2003-2005.   Daskalakis ZJ, Paradiso GO, Christensen BK, Fitzgerald PB, Gunraj C, Chen R. Exploring the connectivity between the cerebellum and the motor cortex in humans. Journal of Physiology (Lond). 2004 Jun 1;557(Pt 2):689-700.   Daskalakis ZJ, Christensen BK, Fitzgerald PB, Rochan L, Chen R. The Mechanisms of Interhemispheric Inhibition in the Human Motor Cortex. Journal of Physiology (Lond). 2002 543: 317-326.   Daskalakis ZJ, Christensen BK, Chen R, Fitzgerald PB, Zipursky RB, Kapur S. Evidence for Impaired Cortical Inhibition in Schizophrenia Using Transcranial Magnetic Stimulation. Archives of General Psychiatry. 2002; 59(4):347-354.
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