Scientific Staff Profiles

This page allows you to read information about people engaged in research at CAMH. You can search for researchers using the name or keyword search engine below.

Dr. Bruce G. Pollock Centre for Addiction and Mental Health 33 Russell Street Toronto, ON M5S 2S1 (416) 535-8501 bruce_pollock@camh.net Dr. Bruce Pollock is the Vice President of Resarch, and a Senior Scientist with the Geriatric Program at CAMH. He is the Sandra A. Rotman Chair in Neuropsychiatry, and Head of the Division of Geriatric Psychiatry with the Faculty of Medicine at the University of Toronto. Search again?
Areas of Research Dr. Pollock is internationally recognized for his work in geriatric clinical psychopharmacology. His overarching research objective is improved therapeutic approaches to geriatric care and his work includes clinical studies examining neurochemical selectivity, pharmacokinetics, and neurophysiological-therapeutic effects of conventional or newly derived/modified agents for the treatment of depression and the behavioural disturbances of dementia.
Publications Bigos KL, Pollock BG, Coley KC, Miller DD, Marder SR, Aravagiri M, Kirshner MA, Bies RR, Sex, race, and smoking impact olanzapine exposure J Clin Pharmacol  48:157-165, 2008. Lotrich FE, Pollock BG,Kirshner M, Ferrell RF, Reynolds CF: Serotonin transporter genotype interacts with paroxetine plasma levels to influence depression treatment response J Psychiatry Neurosci 33: 123-130, 2008. Andreescu C, Mulsant BH, Houck PR, Whyte EM, Mazumdar S, Dombrovski AY,  Pollock BG, Reynolds CF: Empirically derived decision trees for the treatment  of late-life  depression  Am J Psychiatry 165: 855-862, 2008.   Bigos KL Pollock BG, Aizenstein HJ, Fisher PM, Bies RR, Hariri AR: Acute 5-HT reuptake blockade potentiates human amygdala reactivity. Neuropsychopharmacology 33: 3221-3225, 2008. Salzman C, Jeste D, Meyer RE, Cohen-Mansfield J, Cummings J, Grossberg G, Jarvik L, Kraemer H, Laughren T, Lebowitz BD, Maslow K, Niederehe G, Pollock BG, Raskind M, Schultz S, Wang P, Zito JM, Zubenko GS: Elderly Patients with dementia-related symptoms of severe agitation and aggression: Consensus statement on treatment options, clinical trials methodology, and policy. J Clin Psychiatry 69: 889-898, 2008 Chew ML, Mulsant BH, Pollock BG, Lehman ME, Greenspan A, Mahmoud RA, Kirshner MA, Sorisio DA, Bies RR, Gharabawi G: Anticholinergic Activity of 107 Medications Commonly Used by Older Adults. J Am Geriatrics Assoc, 56: 1333-1341, 2008. Whyte EM, Lenze EJ, Butters MA, Skidmore E, Koenig K, Dew MA, Penrod L, Mulsant BH, Pollock BG, Cabacungan L, Begley A, Reynolds CF III, Munin MC: A clinical trial of donepezil and galantamine in the treatment of post-stroke cognitive impairment in the medically rehabilitating elderly. Cerebrovasc Dis 26: 317-321, 2008. Hazra M, Sproule B, Pollock BG: Desvenlafaxine  Drugs of Today 44: 475-487, 2008. Lenze E, Sheffrin M, Driscoll P, Mulsant B, Pollock BG, Lotrich FE, Devlin B, Bies R, Reynolds CF: Incomplete response in late-life depression: Getting to remission. Dialogues in Clinical Neuroscience 10: 301-314, 2008. Frank E, Cassano GB, Rucci P, Fagiolini A, Maggi L, Kraemer HC,  Kupfer DJ, Pollock BG, Bies RR, Nimgaonkar V, Pilkonis P, Shear MK, Grochocinski VJ, Scocco P, Buttenfield J, Forgione RN: Overcoming the Challenges of a Cross-National Investigation: Lessons from the Pittsburgh-Pisa Study of Treatment-Relevant Phenotypes of Unipolar Depression.Clinical Trials 5: 253-261, 2008. Frank E, Cassano GB, Rucci P, Fagiolini A, Maggi L, Kraemer HC,  Kupfer DJ, Pollock BG, Bies RR, Nimgaonkar V, Pilkonis P, Shear MK, Grochocinski VJ, Scocco P, Buttenfield J, Forgione RN: Overcoming the Challenges of a Cross-National Investigation: Lessons from the Pittsburgh-Pisa Study of Treatment-Relevant Phenotypes of Unipolar Depression. Clinical Trials 5: 253-261, 2008. Nebes RD, Pollock BG, Halligan EM, Kirshner MA, Houck PR: Serum anticholinergic activity and motor performance in the elderly. Journal of Gerontology: Medical Sciences 62A: 83-85, 2007. Andreescu C, Lenze EJ, Dew MA, Begley AE, Mulsant BH, Dombrovski AY, Pollock BG, Stack J, Miller MD, Reynolds CF:Effect of comorbid anxiety on treatment response and relapse risk in late-life depression: controlled study. Br J Psychiatry 190: 344-349, 2007. Dew MA, Whyte EM, Lenze EJ, Houck PR, Mulsant BH, Butters MA, Pollock BG, Stack JA, Bensasi S, Reynolds CF: Recovery from major depression in older adults receiving augmentation of antidepressant pharmacotherapy. Am J Psychiatry 164:892-899, 2007.  Muldoon MF, Mackey RH, Sutton-Tyrrell K, Flory JD, Pollock BG, Manuck SB:Lower central serotonergic responsivity is associated with preclinical carotid artery atherosclerosis. Stroke 38:2228-2233, 2007. Lotrich FE, Rabinovitz F, Gironda P, Pollock BG: Depression following pegylated interferon-alpha: characteristics and vulnerability.  J Psychosomatic Research 63: 131-5, 2007. Dombrovski AY, Lenze EJ, Dew MA, Mulsant BH, Pollock BG, Houck PR. Reynolds CF: Maintenance treatment for old-age depression preserves health-related quality of life: A randomized, controlled trial of paroxetine and interpersonal psychotherapy. J Am Geriatr Soc 55:1325–1332,2007. Aravagiri M, Marder SR, Pollock BG: Determination of ziprasidone in human plasma by liquid chromatography-electrospray tandem mass spectrometry and its application to plasma level determination in schizophrenia patients. J Chromatogr B Analyt Technol Biomed Life Sci 847:237-244, 2007. Chow TW, Pollock BG, Milgram NW: Potential cognitive enhancing and disease modificationeffects of SRIs for Alzheimer’s disease. Neuropsychiatric Disease and Treatment 3:627-636, 2007. Pollock BG, Mulsant BH, Rosen J, Mazumdar S, Blakesley RE, Houck PR, Huber KA: A double-blind comparison of citalopram and risperidone for the treatment of behavioral and psychotic symptoms associated with dementia Am J Geriatr Psychiatry 15: 942-952,2007. Szanto K, Mulsant BH, Houck PR, Dew MA, Dombrovski A, Pollock BG, Reynolds CF:Emergence, persistence, and resolution of suicidal Ideation during Treatment of depression in old age.  J Affective Disord 98: 153 – 161, 2007.  Carnahan RM, Lund BC, Perry PJ, Pollock BG, Culp KR. The anticholinergic drug scale as a measure of anticholinergic burden: associations with serum anticholinergic activity. J Clin Pharmacol. 2006:46:1481-1486. Bigos KL, Bies RR, Pollock BG. Population pharmacokinetics in geriatric psychiatry. Am J Geriatric Psychiatry. 2006;14:993-1003. Chew ML, Mulsant BH, Pollock BG, Lehman ME, Greenspan A, Kirshner MA, Bies RR, Kapur S, Gharabawi G. A model of anticholinergic activity of atypical antipsychotic medications. Schizophrenia Res. 2006;88:63-72. Reynolds CF, Buysse DJ, Miller MD, Pollock BG, Hall M, Mazumdar S. Paroxetine treatment of primary insomnia in older adults. Am J Geriatr Psychiatry. 2006;4:803-807. Johnson E, Whyte EM, Mulsant BH, Pollock BG, Begley AE, Weber E, Reynolds CF. Cardiovascular changes associated with venlafaxine in the treatment of late-life depression. Am J Geriatr Psychiatry. 2006;14: 796-802. Lotrich FE, Bies RR, Smith GS, Pollock BG. Relevance of assessing drug concentration exposure in pharmacogenetic and imaging studies. J Psychopharmacology. 2006;20(4 Suppl):33-40. Whyte E, Mulsant BH, Kirshner M, Begley AE, Romkes M, Pollock BG. CYP2D6 Genotype and Venlafaxine-XR concentrations in the depressed elderly. Int J Geriatr Psychiatry. 2006;21: 542-549. Pomara N, Doraiswamy PM, Willoughby L, Mulsant BH. Mehta PD, Reynolds C, Pollock BG. Elevation in plasma Abeta42 in geriatric depression - A pilot study. Neurochem Res. 2006;3: 341-9. Fabian TJ, Schwartzman DS, Ujhelyi MR, Corey SE, Bigos KL, Pollock BG, Kroboth PD. Decreasing pain and anxiety associated with patient-activated atrial shock: A placebo-controlled study of adjunctive sedation with oral triazolam. J Cardiovasc Electrophysiol. 2006;17: 391-5. Bhalla RK, Butters MA, Mulsant BH, Begley AE, Zmuda MD, Schoderbek B, Pollock BG, Reynolds CF, Becker JT. Persistence of neuropsychological deficits in the remitted state of late-life depression. Am J Geriatr Psychiatry. 2006;14: 419-427.
Search again?

• Print