Research

Scientific Staff Profiles

This page allows you to read information about people engaged in research at CAMH. You can search for researchers using the name or keyword search engine below.

Dr. Allan Kaplan

Centre for Addiction and Mental Health
1001 Queen Street West
Toronto, Ontario      M6J 1H4
For Dr. Kaplan, contact Beverly Hamilton
416-535-8501 ext. 6947
beverly_hamilton@camh.net

Dr. Kaplan is the Director of Research Training and a Senior Clinician-Scientist in CAMH's Mood and Anxiety Program. He is also the Loretta Anne Rogers Chair in Eating Disorders at the University Health Network, and Director of the Clinician Scientist Training Program, Vice Chairman of Research and Professor of Psychiatry at the University of Toronto.

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Areas of Research

Dr. Kaplan has focused his research on the psychobiology of anorexia nervosa (AN) and bulimia nervosa (BN). This has included research on the medical complications of AN and BN as well as the neuroendocrinology of these disorders. More recently he has focused his work on neurotransmitter abnormalities in both the serotonergic and dopaminergic sytems in BN and AN.

Dr. Kaplan has also developed and rigorously evaluated innovative treatments such as day hospitalization and community based treatments for eating disorders, and examined predictors of outcome in AN and BN. He has also conducted randomized controlled trials evaluating relapse prevention strategies for AN utilizing cognitive behaviour therapy and fluoxetine.

More recently Dr. Kaplan has conducted research as part of a large multi-site consortium evaluating the genetics of AN and BN utilizing linkage analyses and candidate gene analyses. In collaboration with other investigators at CAMH, Dr. Kaplan’s research has examined genetic factors in weight regulation and caloric intake in obese and non-obese binge eaters.


Publications

Bulik CM, Bacanu SA, Klump KA, Fichter MM, Halmi KA, Keel P, Kaplan AS, Mitchell JE, Rotondo A, Strober M, Treasure J, Woodside DB, Bergen A, Berrettini W, Devlin BD, Kaye WH. Selection of eating disorders phenotypes for linkage analysis. Am J Med Genet B Neuropsychiatr Genet. 5;139(1):81-7, 2005.

Kaplan AS. From Genes to Treatment Response: New Research into the Psychobiology of Anorexia Nervosa. International Journal of Eating Disorders, 37: 3 pp 1-3, 2005.

Levitan RD, Kaplan AS, Masellis M, Basile VS, Richter MA, Kennedy JL. The serotonin-1Dbeta receptor gene and severity of obsessive-compulsive disorder in women with bulimia nervosa. Eur Neuropsychopharmacol. 16(1):1-6, 2006.

Walsh BT, Kaplan AS, Attia E, Olmsted M, Parides M, Carter JC, Pike KM, Devlin MJ, Woodside B, Roberto CA, Rockert W. Fluoxetine after weight restoration in anorexia nervosa: a randomized controlled trial. JAMA. 295(22):2605-12, 2006.

Shroff H, Reba L, Thornton LM, Tozzi F, Klump KL, Berrettini WH, Brandt H, Crawford S, Crow S, Fichter MM, Goldman D, Halmi KA, Johnson C, Kaplan AS, Keel P, LaVia M, Mitchell J, Rotondo A, Strober M, Treasure J, Woodside DB, Kaye WH, Bulik CM. Features associated with excessive exercise in women with eating disorders. Int J Eat Disord.39(6):454-61, 2006.

Anzengruber D, Klump KL, Thornton L, Brandt H, Crawford S, Fichter MM, Halmi KA, Johnson C, Kaplan AS, Lavia M, Mitchell J, Strober M, Woodside DB, Rotondo A, Berrettini WH, Kaye WH, Bulik CM. Smoking in eating disorders. Eat Behav. 7(4):291-9, 2006.

Tozzi, F, Thornton, LM, Mitchell, J, Brandt, H, Crawford, S, Crow, S, Fichter, MM, Goldman, D, Halmi, KA, Johnson, C, Kaplan, AS, Keel, P, LaVia, M, Lilenfed, LR, Plotnicov, K, Pollice, C, Reba, L, .Rotondo, A, Strober, M, Woodside, DB, Berrettini, WH, Kaye, WH, Bulik, CM. Features associated with laxative abuse in individuals with eating disorders. Psychosom Medicine 68(3); 470-477, 2006.

Levitan RD, Masellis M, Lam RW, Kaplan AS, Davis C, Tharmalingam S, Mackenzie B, Basile VS, Kennedy JL. A Birth-Season/DRD4 Gene Interaction Predicts Weight Gain and Obesity in Women with Seasonal Affective Disorder: A Seasonal Thrifty Phenotype Hypothesis. Neuropsychopharmacology. 11: 2504, 2006.

Fernandez-Aranda F, Pinheiro A, Tozzi F, Thornton LM, Fichter M, Halmi KA, Kaplan AS, Klump KL, Strober M, Woodside B, Crow S, Mitchell JE, Rotundo A, Keel P, Plotnicov KH, Berrettini W, Kaye W, Crawford SF, Johnson C, Brandt H, LaVic M, Bulik CM. Symptom profile of major depressive disorder in females with eating disorders. Aust NZ J Psychiatry, 13:57, pp 23-31, 2007.

Pinheiro AP, Thornton LM, Plotonicov KH, Tozzi F, Klump KL, Berrettini WH, Brandt H, Crawford S, Crow S, Fichter MM, Goldman D, Halmi KA, Johnson C, Kaplan AS, Keel P, Lavia M, Mitchell J, Rotondo A, Strober M, Treasure J, Woodside B, Kaye WH, Bulik CM. Patterns of Menstrual Disturbance in Eating Disorders. International Journal of Eating Disorders,40(5),424-434, 2007.

Davis C, Levitan R, Kaplan AS, Carter J, Reid C, Curtis C, Patte K, Kennedy J. Dopamine transporter gene (DAT1) associated with appettite suppression to methylphenidate in a case-control study of binge eating disorder. Neuropsychopharmacology, Feb 2007.

Federici A, Kaplan A. The patient's account of relapse and recovery in anorexia nervosa: a qualitative study. European Journal of Eating Disorders, July 27, 2007.

Rockert W, Kaplan AS, Olmsted MP. Eating Disorder Not Otherwise Specified: The View From a Tertiary Care Center. International Journal of Eating Disorders, Volume 40, Issue S3, Pages: S99-S103, November 2007.

Kaplan AS, Levitan R, Yilmaz Z, Davis C, Tharmalingam S, Kennedy J. A DRD4/BDNF Gene-Gene Interaction Associated with Maximum BMI in Women with Bulimia Nervosa. International Journal of Eating Disorders, in press

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Content updated: April 30, 2007 11:19 AM