Scientific Staff Profiles

This page allows you to read information about people engaged in research at CAMH. You can search for researchers using the name or keyword search engine below.

Dr. Jose N. Nobrega Neuroimaging Section Centre for Addiction and Mental Health 250 College St, Room 271 Toronto, Ontario M5T 1R8 (416) 535-8501 ext. 6259 jose_nobrega@camh.net Dr. Jose N. Nobrega is a Senior Scientist and Head of the Neuroimaging Section in the Neuroscience Department. He is an Associate Professor with the Departments of Psychiatry, Psychology, and Pharmacology at the University of Toronto. Search again?
Areas of Research Dr. Nobrega's research is aimed at mapping changes in specific brain areas as well as the neuroanatomical pathways and chemical mechanisms in neuropsychiatric disorders. The visualization and quantification of neurochemical processes in animal models is providing insight into how brain cells function. Dr. Nobrega is investigating a number of areas including: brain changes associated with cognitive function, movement disorders and depressive states; brain effects of sleep deprivation and other types of stress; the mechanism of action of successful antidepressant interventions; and also, the mechanism of action of antipsychotic drugs, including their side effects.
Publications Schenberg EE, Ferreira TL, Hipólide DC, Nobrega JN, Oliveira MGM. Fear conditioning performance and NMDA receptor subtypes: NR2A differential expression in the striatum. Brain Res Bulletin. 2006;69, 440-446. D’Almeida V, Hipólide DC, Raymond R, Barlow KL, Parkes J-H, Pedrazzoli M, Tufik S, Nobrega JN. Opposite effects of sleep rebound on orexin OX1 and OX2 receptor expression in rat brain. Molecular Brain Research. 2005;136, 148-157. Nobrega JN, Barlow KL, Raymond R, Richter A. Decreased adenosine receptor binding in brains of dystonic dtsz mutant hamsters. Neuroscience. 2005;134, 33-38. Turrone P, Remington G, Kapur S, Nobrega JN. Continuous but not intermittent olanzapine infusion gives rise to vacuous chewing movements (VCMS) in rats. Biological Psychiatry. 2005; 57, 406-411. Setnik B, Nobrega JN. Long-chain acyl-CoA synthetase-2 mRNA: Increased cerebral cortex expression in an animal model of depression, Progress in Neuropsychopharmacology and Biological Psychiatry. 2004;28: 577-582. Turrone P, Remington G, Kapur S, Nobrega JN. Differential effects of continuous versus transient dopamine D2 receptor occupancy in the development of vacuous chewing movements (VCMs) in rats. Neuropsychopharmacology. 2003;28, 1433-1439. Turrone P, Remington G, Nobrega JN. The vacuous chewing movement (VCM) model of tardive dyskinesia revisited: is there a relationship to dopamine D2 receptor occupancy? Neuroscience and Biobehavioral Reviews; 2002;26, 361-380.
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