Scientific Staff Profiles

This page allows you to read information about people engaged in research at CAMH. You can search for researchers using the name or keyword search engine below.

Dr. Benoit H. Mulsant Physician-in-Chief Clinical Director, Geriatric Mental Health Program Centre for Addiction and Mental Health 1001 Queen Street West Toronto, Ontario M6J 1H4  (416) 535-8501 ext. 3656 benoit_mulsant@camh.net Dr. Benoit Mulsant is CAMH's Physician-in-Chief as well as the Clinical Director of the Geriatric Mental Health Program in the Clinical Research Department. He is a Professor in the Department of Psychiatry with the Faculty of Medicine at the University of Toronto. Search again?
Areas of Research Dr. Mulsant has been designing and conducting clinical trials for “hard–to-treat” older patients with mood disorders for more than 15 years. He is concerned about the demographics of an ageing population and the urgency to improve the treatment of seniors with severe mental disorders. He is one of the principal investigators of two major studies: a large placebo-controlled study to investigate the efficacy and tolerability of a combination of a newer antidepressant and an atypical antipsychotic for the treatment of psychotic depression; and the first randomized clinical trial to investigate the efficacy and tolerability of drug therapy for bipolar disorder in late life. In addition, Dr. Mulsant is assessing the nature and course of cognitive impairment in older patients with a psychiatric disorder. He is also involved with a pilot project that uses PET-imaging to investigate how to improve the treatment of late-life schizophrenia.
Publications Chew ML, Mulsant BH, Pollock BG, Lehman M, Greenspan A, Kirshner MA, Bies RR, Kapur S, Gharabawi G. A model of anticholinergic activity of atypical antipsychotic medications. Schizophrenia Research. 2006;88(1):63-72. Mulsant BH, Houck PR, Gildengers AG, Andreescu C, Dew MA, Pollock BG, Miller MD, Stack J, Mazumdar S, Reynolds CF. What is the optimal duration of a short-term antidepressant trial when treating geriatric depression? Journal of Clinical Psychopharmacology. 2006;26(2):113-120. Reynolds CF III, Dew MA, Pollock BG, Mulsant BH, Frank E, Miller MD, Houck PR, Mazumdar S, Butters MA, Stack JA. Schlernitzauer MA, Whyte EM, Gildengers A, Karp J, Lenze E, Szanto K, Bensasi S, Kupfer DJ. Maintenance treatment of major depression in old age. New England Journal of Medicine. 2006;354(11):1130-1138. Mulsant BH, Gharabawi GM, Bossie CA, Mao L, Martinez RA, Tune LE, Greenspan AJ, Bastean JN, Pollock BG. Correlates of anticholinergic activity in patients with dementia and psychosis treated with risperidone or olanzapine. Journal of Clinical Psychiatry. 2004;65(12):1708-1714. Szanto K, Mulsant BH, Houck P, Dew MA, Reynolds CF III. Occurrence and course of suicidality during acute treatment of late-life depression. Archives of General Psychiatry. 2003;60:610-617. Mulsant BH, Pollock BG, Kirshner M, Shen C, Dodge H, Ganguli M. Serum anticholinergic activity in a community-based sample of older adults. Archives of General Psychiatry. 2003;60:198-203. Mulsant BH, Kastango KB, Rosen J, Stone RA, Mazumdar S, Pollock BG. Interrater reliability in clinical trials of depressive disorders. American Journal of Psychiatry. 2002;159:1598-1600. Mulsant BH, Sweet RA, Rosen J, Pollock BG, Flynn T, Begley AE, Mazumdar S, Reynolds CF. A double-blind randomized comparison of nortriptyline plus perphenazine versus nortriptyline plus placebo in the treatment of psychotic depression in late life. Journal of Clinical Psychiatry. 2001;62:597-604. Sackeim HA, Haskett RF, Mulsant BH, Thase ME, Mann JJ, Pettinati HM, Greenberg RM, Crowe RR, Cooper TB, Prudic J. Continuation pharmacotherapy in the prevention of relapse following electroconvulsive therapy. Journal of the American Medical Association. 2001;285(10):1299-1307. Mulsant BH, Alexopoulos GS, Reynolds CF, Katz IR, Abrams R, Oslin D, Schulberg HC. Pharmacological treatment of depression in older primary care patients: the PROSPECT algorithm. International Journal of Geriatric Psychiatry. 2001;16:585-592.
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