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In the following table the methylation data from chr 21/22 tiling arrays (Schumacher et al., 2005) are available. The graphs
are in a format readable by the UCSC Genome browser. The Genome Browser zooms and scrolls over chromosomes, showing the data in a seperate track next to CpG islands, CpG density,
known genes and transcriptome data. By clicking on the links, the Genome browser opens automatically, displaying a specific
area of chromosomes 21 or 22 (browser start position). From there, the sequence can be explored up- and downstream. The dark
red graphs of the custom track on top represent the enrichment of hypo(unmethylated) DNA fragments. An example is displayed
to the right. An absence of bars may represent hypermethylation of that region/CpG island.
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Note: The maps are relatively large, so depending on your internet speed, loading time may take several seconds (cable), 20s-1
min (DSL) up to several minutes (56k). |