Mood stabilizers: Is age an issue?
From: Understanding psychiatric medications: Mood stabilizers - Information for consumers, families and friends (© 2009 CAMH)
Children and teens
The first signs of bipolar disorder can appear in childhood, usually as depression or behaviour problems. Early substance
use problems or petty crime can also be signs. When bipolar disorder in childhood is misdiagnosed as attention-deficit/hyperactivity
disorder or unipolar depression, treatment with stimulants or antidepressants can worsen symptoms.
Mood stabilizers were developed and tested on adults. While most of these drugs are not officially approved for use by children
and teens, professional guidelines direct their use in this age group. Lithium is approved for treating manic symptoms in
children aged 12 and older.
Children and teens may be more prone to the side-effects of these drugs and should be monitored by their doctor regularly
for side-effects.
Older adults
As people age into their 60s and older, their bodies become less able to eliminate medications. This means that older people
who take mood stabilizers need to have the drug levels in their blood measured more often than younger people. Those taking
lithium also need to have their kidney and thyroid function and heart rate monitored more frequently.
As people get older, they also become more sensitive to medications and may require a lower dose. Mood stabilizers can increase
the risk of falls, especially when taken with other drugs.

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